Dose Escalation in Neoadjuvant Chemoradiotherapy for Rectal Cancer: Short-Term Efficacy and Toxicity of VMAT–SIB vs. 3D-CRT

Dose Escalation in Neoadjuvant Chemoradiotherapy for Rectal Cancer: Short-Term Efficacy and Toxicity of VMAT–SIB vs. 3D-CRT

<i>Background and Objectives</i>: The standard treatment for locally advanced rectal cancer (LARC) includes neoadjuvant chemoradiotherapy (nCRT), followed by surgery with or without adjuvant chemotherapy (CT). This study evaluated the efficacy and safety of dose-escalated radiotherapy (R...

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Main Authors: Suzana Stojanovic-Rundic, Mladen Marinkovic, Aleksandra Stanojevic, Dusica Gavrilovic, Radmila Jankovic, Natasa Maksimovic, Aleksandar Tomasevic, Predrag Petrasinovic, Sandra Radenkovic, Milena Cavic
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Medicina
Subjects:
locally advanced rectal cancer
neoadjuvant chemoradiotherapy
dose escalation
radiotherapy techniques
simultaneous integrated boost
sphincter preservation
Online Access:https://www.mdpi.com/1648-9144/61/3/483
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