AI-integrated IQPD framework of quality prediction and diagnostics in small-sample multi-unit pharmaceutical manufacturing: Advancing from experience-driven to data-driven manufacturing

AI-integrated IQPD framework of quality prediction and diagnostics in small-sample multi-unit pharmaceutical manufacturing: Advancing from experience-driven to data-driven manufacturing

The pharmaceutical industry faces challenges in quality digitization for complex multi-stage processes, especially in small-sample systems. Here, an intelligent quality prediction and diagnostic (IQPD) framework was developed and applied to Tong Ren Tang's Niuhuang Qingxin Pills, utilizing four...

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Bibliographic Details
Main Authors: Kaiyi Wang, Xinhai Chen, Nan Li, Huimin Feng, Xiaoyi Liu, Yifei Wang, Yanfei Wu, Yufeng Guo, Shuoshuo Xu, Lu Yao, Zhaohua Zhang, Jun Jia, Zhishu Tang, Zhisheng Wu
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Smart manufacturing
Artificial intelligence
Intelligent quality prediction and diagnostics
Small-sample multi-unit manufacturing
Data-driven manufacturing
Real-world Tong Ren Tang's Niuhuang Qingxin Pills
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383525003806
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