Systemic inflammatory response in colorectal cancer is associated with tumour mismatch repair and impaired survival

Systemic inflammatory response in colorectal cancer is associated with tumour mismatch repair and impaired survival

Abstract The systemic inflammatory response (SIR), defined as elevated levels of circulating C-reactive protein (CRP), is an important predictor of impaired survival in colorectal cancer. The aim of this study was to explore the prognostic role of SIR and its association with tumour mismatch repair...

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Main Authors: Mats Hjortborg, Sofia Edin, Camilla Böckelman, Tuomas Kaprio, Xingru Li, Ioannis Gkekas, Jaana Hagström, Karin Strigård, Caj Haglund, Ulf Gunnarsson, Richard Palmqvist
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Colorectal cancer
Systemic inflammatory response
Mismatch repair
Immunity
Prognosis
Online Access:https://doi.org/10.1038/s41598-024-80803-6
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https://doi.org/10.1038/s41598-024-80803-6

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