Predicting novel candidate human obesity genes and their site of action by systematic functional screening in Drosophila.
The discovery of human obesity-associated genes can reveal new mechanisms to target for weight loss therapy. Genetic studies of obese individuals and the analysis of rare genetic variants can identify novel obesity-associated genes. However, establishing a functional relationship between these candi...
Saved in:
| Main Authors: | Neha Agrawal, Katherine Lawler, Catherine M Davidson, Julia M Keogh, Robert Legg, INTERVAL, Inês Barroso, I Sadaf Farooqi, Andrea H Brand |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2021-11-01
|
| Series: | PLoS Biology |
| Online Access: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3001255&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila melanogaster
by: Ruchi Umargamwala, et al.
Published: (2025-04-01) -
Drosophila as a replacement model to study candidate genes involved in cardiac physiology
by: Kate Campbell, et al.
Published: (2024-11-01) -
Stability and dynamics of polycomb target sites in Drosophila development.
by: Camilla Kwong, et al.
Published: (2008-09-01) -
An appetite for research: an interview with Sadaf Farooqi
by: Sadaf Farooqi
Published: (2025-04-01) -
Large-scale turnover of functional transcription factor binding sites in Drosophila.
by: Alan M Moses, et al.
Published: (2006-10-01)