Predicting novel candidate human obesity genes and their site of action by systematic functional screening in Drosophila.

The discovery of human obesity-associated genes can reveal new mechanisms to target for weight loss therapy. Genetic studies of obese individuals and the analysis of rare genetic variants can identify novel obesity-associated genes. However, establishing a functional relationship between these candi...

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Bibliographic Details
Main Authors: Neha Agrawal, Katherine Lawler, Catherine M Davidson, Julia M Keogh, Robert Legg, INTERVAL, Inês Barroso, I Sadaf Farooqi, Andrea H Brand
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-11-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3001255&type=printable
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