Neuroprotective effects of melanins and melanin derivatives from Calvatia Craniiformis and Xylaria plebeja against Parkinsonian toxins

Abstract Fungal melanins have remarkable bioactivities, but their practical applications are limited, partly due to their hydrophobic nature. Melanin modification with amino acids was reported to improve their water solubility. This research aimed to extract, and modify the melanins from Calvatia cr...

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Main Authors: Duong Thuy Nguyen, Linh Phuong Nguyen Vo, Debby Mangelings, Ann Van Eeckhaut, Yvan Vander Heyden, Hanh T. M. Tran
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-90557-4
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