Ovatodiolide triggers ferroptosis in high-grade serous ovarian cancer through HMOX1 upregulation

High-grade serous ovarian carcinoma (HGSC) is the most aggressive and lethal gynecological malignancy, largely due to its asymptomatic early stages and late-stage diagnosis. Current standard treatments involve surgical resection combined with platinum-based chemotherapy, yet recurrence rates remain...

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Bibliographic Details
Main Authors: Yew-Min Tzeng, Aye Aye Khine, Hsuan-Shun Huang, Tang-Yuan Chu
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Molecular Therapy: Oncology
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Online Access:http://www.sciencedirect.com/science/article/pii/S295032992500092X
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