Senecavirus a can replicate in apical-out porcine intestinal organoids and induce stress granules and innate immune response

Senecavirus a can replicate in apical-out porcine intestinal organoids and induce stress granules and innate immune response

Senecavirus A (SVA) causes clinical blistering and ulcerative lesions resembling foot-and-mouth disease (FMD), often with mixed infections that exacerbate the disease and impact pig industry development. SVA has been demonstrated to induce diarrhea, dehydration and mortality in piglets. However, the...

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Bibliographic Details
Main Authors: Ying Wang, Zhiying Wei, Jiaxuan Li, Xiaona Wang, Yanping Jiang, Wen Cui, Zhifu Shan, Lijie Tang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Virulence
Subjects:
SVA
intestinal organoids
replication
stress granules
3D culture
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2025.2548623
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https://www.tandfonline.com/doi/10.1080/21505594.2025.2548623

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