Peripheral Blood T‐Cell Receptor Repertoire Diversity as a Potential Biomarker in the Diagnosis and Treatment Evaluation of Colorectal and Lung Cancers: A Prospective Observational Study

Peripheral Blood T‐Cell Receptor Repertoire Diversity as a Potential Biomarker in the Diagnosis and Treatment Evaluation of Colorectal and Lung Cancers: A Prospective Observational Study

ABSTRACT Background T‐cell receptor (TCR) diversity 50 (D50) values could assess peripheral blood (PB) TCR diversity and immunity. This study aimed to evaluate the potential D50 value in the diagnosis and treatment evaluation of colorectal cancer (CRC) and nonsmall‐cell lung cancer (NSCLC). Methods...

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Bibliographic Details
Main Authors: Jilong Ma, Yuanbiao Wang, Zhixin Zhang, Xinyi Cai, Xudong Xiang, Yan Chen, Fengqiong Sun, Jian Dong
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Cancer Medicine
Subjects:
colorectal cancer
neoadjuvant therapy
nonsmall‐cell lung cancer
prospective observational study
TCR repertoire diversity
Online Access:https://doi.org/10.1002/cam4.70937
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https://doi.org/10.1002/cam4.70937

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