Surfactant Protein D and Club Cell Secretory Protein as Biomarkers of Disease Severity and Fostamatinib Efficacy in Severe COVID-19

Surfactant Protein D and Club Cell Secretory Protein as Biomarkers of Disease Severity and Fostamatinib Efficacy in Severe COVID-19

OBJECTIVES:. The objective of the study was to evaluate whether epithelial injury biomarkers—club cell secretory protein (CC16), surfactant protein D (SPD), surfactant protein A (SPA), and receptor for advanced glycation end-products (RAGE)—could prognosticate disease severity and predict treatment...

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Main Authors: Marcos J. Ramos-Benitez, PhD, Rui Miao, PhD, Andrea P. Rivera-Torres, MS, Mercedes Lacourt-Ventura, MS, Sonya J. Malavez-Cajigas, MS, Xin Tian, PhD, Heather L. Teague, PhD, Wilfredo De Jesus-Rojas, MD, Robert Reger, MS, Anthony F. Suffredini, MD, Christopher King, MD, Steven D. Nathan, MD, Richard W. Childs, MD, Jeffrey R. Strich, MD
Format: Article
Language:English
Published: Wolters Kluwer 2025-04-01
Series:Critical Care Explorations
Online Access:http://journals.lww.com/10.1097/CCE.0000000000001252
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http://journals.lww.com/10.1097/CCE.0000000000001252

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