Differential gene expression profiles of pancreatic ductal adenocarcinomas among African American and caucasian American patients

Differential gene expression profiles of pancreatic ductal adenocarcinomas among African American and caucasian American patients

Purpose: In the United States, African Americans (AA) have higher Pancreatic ductal adenocarcinoma (PDAC) incidence and mortality rates than Caucasian Americans (CA). This study aimed to identify distinct gene expression signatures and differentially regulated pathways in AA and CA PDACs. Methods: T...

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Main Authors: Prachi Bajpai, Ravi Paluri, Sameer Al Diffalha, Darshan S Chandrashekar, Farrukh Afaq, Dennis Otali, Amr Elkholy, C. Ryan Miller, Shajan Peter, Ashish Manne, Ganji Purnachandra Nagaraju, Madhu Sudhana Saddala, Moh’d Khushman, Sooryanarayana Varambally, Upender Manne
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Translational Oncology
Subjects:
PDAC
Transcriptomic analyses
Gene expression
Signaling pathways
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523325001974
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