Reporting quality of dose-expansion cohorts in trials of anticancer drugs could be improved: a cross-sectional study

Abstract Background Dose-expansion cohort (DEC) has been increasingly used as the pivotal trial to demonstrate preliminary efficacy and safety of target anticancer drugs. We aimed to investigate the reporting quality in the published articles of DECs. Methods We retrospectively identified the publis...

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Bibliographic Details
Main Authors: Yafang Huang, Jinjia Zhong, Ting Zhu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-025-08909-4
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