IL-10 signaling blockade controls murine West Nile virus infection.

IL-10 signaling blockade controls murine West Nile virus infection.

West Nile virus (WNV), a mosquito-borne single-stranded RNA flavivirus, can cause significant human morbidity and mortality. Our data show that interleukin-10 (IL-10) is dramatically elevated both in vitro and in vivo following WNV infection. Consistent with an etiologic role of IL-10 in WNV pathoge...

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Bibliographic Details
Main Authors: Fengwei Bai, Terrence Town, Feng Qian, Penghua Wang, Masahito Kamanaka, Tarah M Connolly, David Gate, Ruth R Montgomery, Richard A Flavell, Erol Fikrig
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000610&type=printable
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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000610&type=printable

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