Double-filtration plasmapheresis reduces type I interferon bioavailability and inducing activity in systemic lupus erythematosus

Double-filtration plasmapheresis reduces type I interferon bioavailability and inducing activity in systemic lupus erythematosus

Type I interferons (IFN-Is) play a significant role in systemic lupus erythematosus (SLE) pathogenesis. Double-filtration plasmapheresis (DFPP) is a treatment option for SLE; however, its effect on IFN-Is remains unclear. Therefore, we investigated the effects of DFPP on IFN-Is. Plasma from patients...

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Main Authors: Takumi Saito, Ryo Takatsuji, Goh Murayama, Yu Yamaji, Yukitomo Hagiwara, Yujin Nishioka, Taiga Kuga, Tomoko Miyashita, Makio Kusaoi, Naoto Tamura, Ken Yamaji
Format: Article
Language:English
Published: Taylor & Francis Group 2024-10-01
Series:Immunological Medicine
Subjects:
Apheresis
cell-based reporter system
STING pathway
systemic lupus erythematosus
type I interferon
Online Access:https://www.tandfonline.com/doi/10.1080/25785826.2024.2372918
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https://www.tandfonline.com/doi/10.1080/25785826.2024.2372918

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