Pathobiology and Molecular Pathways Implicated in Osteosarcoma Lung Metastasis: A Scoping Review

Osteosarcoma (OS) is the most common primary bone malignancy, with lung metastasis being the leading cause of mortality. The metastatic process is driven by complex biological mechanisms, including tumor cell-specific adaptations of growth pathways, immune modulation within the tumor microenvironmen...

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Bibliographic Details
Main Authors: Ala Bashir MD, Ayden Ismail MD, Avenie Mavadia MD, Aruni Ghose MD, Saak Victor Ovsepian PhD, Stergios Boussios MD, MSc, PhD, FRCP
Format: Article
Language:English
Published: SAGE Publishing 2025-07-01
Series:Technology in Cancer Research & Treatment
Online Access:https://doi.org/10.1177/15330338251359716
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