Genetics and Molecular Pathogenesis of the Chondrosarcoma: A Review of the Literature

Genetics and Molecular Pathogenesis of the Chondrosarcoma: A Review of the Literature

The chondrosarcoma, a cartilage-forming bone tumor, presents significant clinical challenges due to its resistance to chemotherapy and radiotherapy. Surgical excision remains the primary treatment, but high-grade chondrosarcomas are prone to recurrence and metastasis, necessitating the identificatio...

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Bibliographic Details
Main Authors: Georgian-Longin Iacobescu, Antonio-Daniel Corlatescu, Bogdan Serban, Razvan Spiridonica, Horia Petre Costin, Catalin Cirstoiu
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Current Issues in Molecular Biology
Subjects:
chondrosarcoma
biomarkers
genetic alterations
molecular pathways
personalized therapy
Online Access:https://www.mdpi.com/1467-3045/46/11/751
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