Acetylated Dendrobium huoshanense polysaccharide: a novel inducer of apoptosis in colon cancer cells via Fas–FasL pathway activation and metabolic reprogramming

Acetylated Dendrobium huoshanense polysaccharide: a novel inducer of apoptosis in colon cancer cells via Fas–FasL pathway activation and metabolic reprogramming

IntroductionNot all polysaccharides function as antitumor drugs, nor do they universally possess the same advantages regarding safety and biocompatibility. Those polysaccharides that are effective antitumor agents typically demonstrate superior safety profiles and biocompatibility compared to synthe...

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Bibliographic Details
Main Authors: Liang Yao, Chen Gu, Ruipeng Ge, Xiaoqian Zhang, Xinqian Meng, Lei Wang, Daiyin Peng, Guozhuan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Oncology
Subjects:
Dendrobium huoshanense polysaccharide
apoptosis
Fas–FasL signaling pathway
anti-tumor mechanism
metabolic reprogramming
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1529868/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1529868/full

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