Strengthening monocarboxylate transporters by adiponectin receptor agonist ameliorates diabetic peripheral neuropathy

Strengthening monocarboxylate transporters by adiponectin receptor agonist ameliorates diabetic peripheral neuropathy

Abstract Background Disruption of energy support to peripheral nerves leads to dysfunction and degeneration of both neuronal axons and Schwann cells (SCs). Methods We evaluated the effects of the adiponectin receptor (AdipoR) agonist, AdipoRon on diabetic peripheral neuropathy (DPN) using db/db mice...

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Main Authors: Tae Woo Kim, Sae-Jong Oum, Ji Hee Lim, Yaeni Kim, Eun Nim Kim, Yongjie Jin, Yu Ah Hong, Seung Yun Chae, Bum Soon Choi, Hye Won Kim, Cheol Whee Park
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cell Communication and Signaling
Subjects:
Adiponectin
Diabetic peripheral neuropathy
Glucolipotoxicity
Monocarboxylate transporter
Online Access:https://doi.org/10.1186/s12964-025-02326-5
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https://doi.org/10.1186/s12964-025-02326-5

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