In Silico Analysis of Cross-Species Sequence Variability in Host Interferon Antiviral Pathway Proteins and SARS-CoV-2 Susceptibility

Zoonotic transmission of severe acute respiratory coronavirus 2 (SARS-CoV-2) has been found to result in infections in more than 30 mammalian species. The SARS-CoV-2 spike protein binds to the host’s angiotensin converting enzyme 2 (ACE2) cell surface receptor to gain entry into the cell. ACE2 prote...

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Bibliographic Details
Main Authors: Sally A. Mayasich, Peter G. Schumann, Maxwell Botz, Carlie A. LaLone
Format: Article
Language:English
Published: Compuscript Ltd 2024-10-01
Series:Zoonoses
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/ZOONOSES-2024-0028
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