Acute Cardiogenic Shock Induced by Infusional 5-Fluorouracil
A 49-year-old patient with metastatic carcinoma of the bladder and no prior history of heart disease presented with diffuse ST elevation, elevated troponins, and biventricular dysfunction requiring intensive care unit admission and inotropic support after receiving her first course of infusional 5-f...
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Format: | Article |
Language: | English |
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Wiley
2014-01-01
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Series: | Case Reports in Oncological Medicine |
Online Access: | http://dx.doi.org/10.1155/2014/819396 |
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author | Jeffrey Sulpher Franco Dattilo Susan Dent Michele Turek M. Neil Reaume Christopher Johnson |
author_facet | Jeffrey Sulpher Franco Dattilo Susan Dent Michele Turek M. Neil Reaume Christopher Johnson |
author_sort | Jeffrey Sulpher |
collection | DOAJ |
description | A 49-year-old patient with metastatic carcinoma of the bladder and no prior history of heart disease presented with diffuse ST elevation, elevated troponins, and biventricular dysfunction requiring intensive care unit admission and inotropic support after receiving her first course of infusional 5-fluorouracil (5-FU). Over the course of several days, the patient’s cardiac function and clinical status returned to baseline. A follow-up echocardiogram performed 5 days after initial presentation revealed an ejection fraction of 59 percent, with no evidence of wall motion abnormalities. Subsequent 5-FU chemotherapy was discontinued, and the patient went on to receive second-line chemotherapy. |
format | Article |
id | doaj-art-f2416804e86742e2a189223603001370 |
institution | Kabale University |
issn | 2090-6706 2090-6714 |
language | English |
publishDate | 2014-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Oncological Medicine |
spelling | doaj-art-f2416804e86742e2a1892236030013702025-02-03T01:02:43ZengWileyCase Reports in Oncological Medicine2090-67062090-67142014-01-01201410.1155/2014/819396819396Acute Cardiogenic Shock Induced by Infusional 5-FluorouracilJeffrey Sulpher0Franco Dattilo1Susan Dent2Michele Turek3M. Neil Reaume4Christopher Johnson5Division of Medical Oncology, The Ottawa Hospital, Ottawa, ON, K1H 8L6, CanadaDivision of Medical Oncology, The Ottawa Hospital, Ottawa, ON, K1H 8L6, CanadaDivision of Medical Oncology, The Ottawa Hospital, Ottawa, ON, K1H 8L6, CanadaDivision of Cardiology, The Ottawa Hospital, Ottawa, ON, K1H 8L6, CanadaDivision of Medical Oncology, The Ottawa Hospital, Ottawa, ON, K1H 8L6, CanadaDivision of Cardiology, The Ottawa Hospital, Ottawa, ON, K1H 8L6, CanadaA 49-year-old patient with metastatic carcinoma of the bladder and no prior history of heart disease presented with diffuse ST elevation, elevated troponins, and biventricular dysfunction requiring intensive care unit admission and inotropic support after receiving her first course of infusional 5-fluorouracil (5-FU). Over the course of several days, the patient’s cardiac function and clinical status returned to baseline. A follow-up echocardiogram performed 5 days after initial presentation revealed an ejection fraction of 59 percent, with no evidence of wall motion abnormalities. Subsequent 5-FU chemotherapy was discontinued, and the patient went on to receive second-line chemotherapy.http://dx.doi.org/10.1155/2014/819396 |
spellingShingle | Jeffrey Sulpher Franco Dattilo Susan Dent Michele Turek M. Neil Reaume Christopher Johnson Acute Cardiogenic Shock Induced by Infusional 5-Fluorouracil Case Reports in Oncological Medicine |
title | Acute Cardiogenic Shock Induced by Infusional 5-Fluorouracil |
title_full | Acute Cardiogenic Shock Induced by Infusional 5-Fluorouracil |
title_fullStr | Acute Cardiogenic Shock Induced by Infusional 5-Fluorouracil |
title_full_unstemmed | Acute Cardiogenic Shock Induced by Infusional 5-Fluorouracil |
title_short | Acute Cardiogenic Shock Induced by Infusional 5-Fluorouracil |
title_sort | acute cardiogenic shock induced by infusional 5 fluorouracil |
url | http://dx.doi.org/10.1155/2014/819396 |
work_keys_str_mv | AT jeffreysulpher acutecardiogenicshockinducedbyinfusional5fluorouracil AT francodattilo acutecardiogenicshockinducedbyinfusional5fluorouracil AT susandent acutecardiogenicshockinducedbyinfusional5fluorouracil AT micheleturek acutecardiogenicshockinducedbyinfusional5fluorouracil AT mneilreaume acutecardiogenicshockinducedbyinfusional5fluorouracil AT christopherjohnson acutecardiogenicshockinducedbyinfusional5fluorouracil |