Physical training reduces cell senescence and associated insulin resistance in skeletal muscle

Background: Cell senescence (CS) is a key aging process that leads to irreversible cell cycle arrest and an altered secretory phenotype. In skeletal muscle (SkM), the accumulation of senescent cells contributes to sarcopenia. Despite exercise being a known intervention for maintaining SkM function a...

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Bibliographic Details
Main Authors: Agnieszka Podraza-Farhanieh, Rosa Spinelli, Federica Zatterale, Annika Nerstedt, Silvia Gogg, Matthias Blüher, Ulf Smith
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Molecular Metabolism
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Online Access:http://www.sciencedirect.com/science/article/pii/S2212877825000377
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