Inhibition of FTO expression by thiodiphenol impairs Leydig cell maturation in pubertal male rats

This study investigated the multifaceted effects of 4,4’-thiodiphenol (TDP) on male reproductive health, focusing on its toxicity, hormonal modulation, and impact on steroidogenesis. Male rats were exposed to TDP at varying doses (0, 1, 10, and 100 mg/kg) from day 35–56 postpartum. Overt toxicity wa...

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Bibliographic Details
Main Authors: Bingru Zhang, Hehua Quan, Chao Wen, Yingfen Ying, Yang Zhu, Ren-Shan Ge, Qiqi Zhu
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Ecotoxicology and Environmental Safety
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Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325001514
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