Bispecific antibody targeting shared indel-derived neoantigen of APC

T cells play a pivotal role in cancer immunotherapy by recognizing tumor-specific neoantigens presented on HLA molecules, which are specifically expressed on cancer cells. While neoantigens are generally unique to individual cancers, certain neoantigens, known as ‘shared neoantigens’ that are common...

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Bibliographic Details
Main Authors: Clara Effenberger, Xiaojing Wu, Peng Zhao, Saki Matsumoto, Yusuke Nakamura, Kazuma Kiyotani
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1574958/full
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