Investigating Strategies to Enhance the Aqueous Solubility of Ketamine HCl for Intranasal Delivery

Investigating Strategies to Enhance the Aqueous Solubility of Ketamine HCl for Intranasal Delivery

<b>Background:</b> Ketamine HCl, an FDA-approved therapeutic, is administered through various routes, including intranasal delivery. Administering an adequate therapeutic dose of intranasal ketamine HCl is challenging due to the limited volume that can be delivered intranasally given the...

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Bibliographic Details
Main Authors: Sourour Idoudi, Alaaeldin Saleh, Mohammed Akkbik, Leena Amine, Khalid Alansari, Ousama Rachid, Alaaldin M. Alkilany
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceutics
Subjects:
ketamine HCl
solubility
sodium dodecyl sulfate
solvent
intranasal delivery
Online Access:https://www.mdpi.com/1999-4923/16/12/1502
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