Potential drug targets for ovarian cancer identified through Mendelian randomization and colocalization analysis

Abstract Background The existing drugs for ovarian cancer (OC) are unsatisfactory and thus new drug targets are urgently required. We conducted proteome-wide Mendelian randomization (MR) and colocalization analysis to pinpoint potential targets for OC. Methods Data on protein quantitative trait loci...

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Bibliographic Details
Main Authors: Sicong Liu, Hao Lin, Ke Zhang, Quan Zhou, Yang Shen
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Ovarian Research
Subjects:
Online Access:https://doi.org/10.1186/s13048-025-01620-7
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