High glucose induces senescence in synovial mesenchymal stem cells through mitochondrial dysfunction

Abstract Purpose To investigate the impact of high glucose on the senescence of synovial mesenchymal stem cells (SMSCs) and to elucidate the role of mitochondrial dysfunction in this process. Methods ‌SMSCs were treated with medium containing high glucose (25 mmol/L) or low glucose (5.5 mmol/L) conc...

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Bibliographic Details
Main Authors: Shuyi Tan, Wangxi Wu, Yifan Chen, Hai Gao
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Oral Health
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Online Access:https://doi.org/10.1186/s12903-025-05938-y
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