Triple-negative breast cancer modifies the systemic immune landscape and alters neutrophil functionality

Abstract Cancer disrupts intratumoral innate-adaptive immune crosstalk, but how the systemic immune landscape evolves during breast cancer progression remains unclear. We profiled circulating immune cells in stage I–III and stage IV triple-negative breast cancer (TNBC) patients and healthy donors (H...

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Bibliographic Details
Main Authors: Noor A. M. Bakker, Hannah Garner, Ewald van Dyk, Elisa Champanhet, Chris Klaver, Maxime Duijst, Leonie Voorwerk, Iris Nederlof, Rosie Voorthuis, Marte C. Liefaard, Marja Nieuwland, Iris de Rink, Onno B. Bleijerveld, Hendrika M. Oosterkamp, Lodewyk F. A. Wessels, Marleen Kok, Karin E. de Visser
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-025-00721-2
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