Clinical phenotypes in acute and chronic infarction explained through human ventricular electromechanical modelling and simulations

Clinical phenotypes in acute and chronic infarction explained through human ventricular electromechanical modelling and simulations

Sudden death after myocardial infarction (MI) is associated with electrophysiological heterogeneities and ionic current remodelling. Low ejection fraction (EF) is used in risk stratification, but its mechanistic links with pro-arrhythmic heterogeneities are unknown. We aim to provide mechanistic exp...

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Bibliographic Details
Main Authors: Xin Zhou, Zhinuo Jenny Wang, Julia Camps, Jakub Tomek, Alfonso Santiago, Adria Quintanas, Mariano Vazquez, Marmar Vaseghi, Blanca Rodriguez
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-12-01
Series:eLife
Subjects:
cardiac electromechanics
modelling and simulation
post-myocardial infarction
electrocardiogram
multiscale
disease mechanisms
Online Access:https://elifesciences.org/articles/93002
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https://elifesciences.org/articles/93002

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