A direct experimental test of Ohno’s hypothesis

A direct experimental test of Ohno’s hypothesis

Gene duplication drives evolution by providing raw material for proteins with novel functions. An influential hypothesis by Ohno (1970) posits that gene duplication helps genes tolerate new mutations and thus facilitates the evolution of new phenotypes. Competing hypotheses argue that deleterious mu...

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Bibliographic Details
Main Authors: Ljiljana Mihajlovic, Bharat Ravi Iyengar, Florian Baier, Içvara Barbier, Justyna Iwaszkiewicz, Vincent Zoete, Andreas Wagner, Yolanda Schaerli
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-04-01
Series:eLife
Subjects:
gene duplication
mutational robustness
experimental evolution
directed evolution
phenotypic diversity
Online Access:https://elifesciences.org/articles/97216
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https://elifesciences.org/articles/97216

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