Chronic mild stress disrupts mitophagy and mitochondrial status in rat frontal cortex

Abstract Background Mitochondria are very dynamic organelles that maintain cellular homeostasis, crucial in the central nervous system. Mitochondrial abnormalities have been described in neuropsychiatric diseases, namely major depression disorder (MDD) and schizophrenia. Since stress is the predomin...

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Bibliographic Details
Main Authors: Cristina Ulecia-Morón, Álvaro G. Bris, Karina S. MacDowell, José L. M. Madrigal, Borja García-Bueno, Juan C. Leza, Javier R. Caso
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-025-06604-1
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