Analysis of nuclear export sequence regions of FUS-Related RNA-binding proteins in essential tremor.

Analysis of nuclear export sequence regions of FUS-Related RNA-binding proteins in essential tremor.

<h4>Background and objective</h4>Genes encoding RNA-binding proteins, including FUS and TDP43, play a central role in different neurodegenerative diseases such as amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Recently, a mutation located in the nuclear export signa...

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Main Authors: Oswaldo Lorenzo-Betancor, Kotaro Ogaki, Alexandra Soto-Ortolaza, Catherine Labbé, Carles Vilariño-Güell, Alex Rajput, Ali H Rajput, Pau Pastor, Sara Ortega, Elena Lorenzo, Audrey J Strongosky, Jay A van Gerpen, Ryan J Uitti, Zbigniew K Wszolek, Owen A Ross
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0111989
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https://doi.org/10.1371/journal.pone.0111989

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