Astilbin Alleviates Radiation-Induced Pulmonary Fibrosis via <i>circ</i>PRKCE Targeting the TGF-β/Smad7 Pathway to Inhibit Epithelial–Mesenchymal Transition

Astilbin Alleviates Radiation-Induced Pulmonary Fibrosis via <i>circ</i>PRKCE Targeting the TGF-β/Smad7 Pathway to Inhibit Epithelial–Mesenchymal Transition

<b>Purpose:</b> This study aimed to clarify the protective effect of astilbin (AST) on radiation-induced pulmonary fibrosis (RIPF) and explore its underlying molecular mechanism, focusing on non-coding RNAs. <b>Methods:</b> Mouse lung epithelial cells (MLE-12 and TC-1) and C5...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhiling Shi, Jing Liu, Jing Qin, Xian Liang, Xue Ou, Tingting Zhang, Xueting Yan, Qianxin Hu, Weimei Huang, Kai Hu
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Biomedicines
Subjects:
radiation-induced pulmonary fibrosis
astilbin
epithelial–mesenchymal transition
Smad7
radioprotection
Online Access:https://www.mdpi.com/2227-9059/13/3/689
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2227-9059/13/3/689

Similar Items