Plasticity and Co-Factor-Dependent Structural Changes in the RecA Nucleoprotein Filament Studied by Small-Angle X-Ray Scattering (SAXS) Measurements and Molecular Modeling

Plasticity and Co-Factor-Dependent Structural Changes in the RecA Nucleoprotein Filament Studied by Small-Angle X-Ray Scattering (SAXS) Measurements and Molecular Modeling

Structural analyses of protein filaments formed by self-assembly, such as actin, tubulin, or recombinase filaments, have suffered for decades from technical issues due to difficulties in crystallization, their large size, or the dynamic behavior inherent to their cellular function. The advent of cry...

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Bibliographic Details
Main Authors: Satomi Inaba-Inoue, Afra Sabei, Anne-Elisabeth Molza, Mara Prentiss, Tsutomu Mikawa, Hiroshi Sekiguchi, Chantal Prévost, Masayuki Takahashi
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Molecules
Subjects:
RecA nucleofilament
SAXS
helical protein assembly
protein filament plasticity
integrative modeling
Online Access:https://www.mdpi.com/1420-3049/30/8/1793
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