Oxidative Toxicity in Neurodegenerative Diseases: Role of Mitochondrial Dysfunction and Therapeutic Strategies

Besides fluorine, oxygen is the most electronegative element with the highest reduction potential in biological systems. Metabolic pathways in mammalian cells utilize oxygen as the ultimate oxidizing agent to harvest free energy. They are very efficient, but not without risk of generating various ox...

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Bibliographic Details
Main Authors: Katie Facecchia, Lee-Anne Fochesato, Sidhartha D. Ray, Sidney J. Stohs, Siyaram Pandey
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2011/683728
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