Therapeutic potential of miR-133a-transfected bone marrow mesenchymal stem cell transplantation in improving cardiac function post-myocardial infarction

Therapeutic potential of miR-133a-transfected bone marrow mesenchymal stem cell transplantation in improving cardiac function post-myocardial infarction

Abstract Objective The objective of this study is to examine the therapeutic efficacy of miR-133a-transfected bone marrow mesenchymal stem cells (BM-MSCs) in restoring damaged myocardium, reducing myocardial fibrosis, and improving cardiac function following myocardial infarction (MI). Methods Bone...

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Bibliographic Details
Main Authors: Yanglanduo Cao, Xiaohan Chen, Biao Cheng, Xuefei Tao, Wei Zhang, Yong Shi, Jie Gao, Minghuan Fu
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Cardiothoracic Surgery
Subjects:
Cardiac dysfunction
miR-133a transfected stem cells
Myocardial fibrosis
Myocardial infarction
Stem cell survival
Online Access:https://doi.org/10.1186/s13019-025-03367-0
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https://doi.org/10.1186/s13019-025-03367-0

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