A Smart Ru‐Locked Chemiluminescence Probe via Bioorthogonal Activation for Highly Selective, Real‐Time and Noninvasive In Vivo Imaging of Thiol Dysregulation

A Smart Ru‐Locked Chemiluminescence Probe via Bioorthogonal Activation for Highly Selective, Real‐Time and Noninvasive In Vivo Imaging of Thiol Dysregulation

ABSTRACT Bioorthogonal cleavage chemistry (BCC) has been extensively applied to fluorescence‐based imaging in cancer diagnostics. Its potential in chemiluminescence imaging is to be explored. In this study, a smart ruthenium (Ru)‐catalyzed bioorthogonal activation chemiluminescence (BAC) probe is de...

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Bibliographic Details
Main Authors: Dongnan Guo, Dan Xu, Xiaofeng Wei, Chunying Fan, Bobo Wang, Laifu Li, Haixia Song, Wenguang Yang, Yujie Wang, Zhaojia Wang, Xiaofang Hou, Sicen Wang
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Aggregate
Subjects:
bioorthogonal chemistry
chemiluminescence
dioxetanes
in vivo imaging
ruthenium catalyst
Online Access:https://doi.org/10.1002/agt2.70076
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https://doi.org/10.1002/agt2.70076

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