Regulation of nc886 (vtRNA2-1) RNAs is associated with cardiometabolic risk factors and diseases

Regulation of nc886 (vtRNA2-1) RNAs is associated with cardiometabolic risk factors and diseases

Abstract Non-coding 886 (nc886 , vtRNA2-1) is a polymorphically imprinted gene. The methylation status of this locus has been shown to be associated with periconceptional conditions, and both the methylation status and the levels of nc886 RNAs have been shown to associate with later-life health trai...

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Main Authors: Sonja Rajić, Thomas Delerue, Justiina Ronkainen, Ruiyuan Zhang, Joanna Ciantar, Daria Kostiniuk, Pashupati P. Mishra, Leo-Pekka Lyytikäinen, Nina Mononen, Laura Kananen, Annette Peters, Juliane Winkelmann, Marcus E. Kleber, Stefan Lorkowski, Mika Kähönen, Terho Lehtimäki, Olli Raitakari, Melanie Waldenberger, Christian Gieger, Winfried März, Emily W. Harville, Sylvain Sebert, Saara Marttila, Emma Raitoharju
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Clinical Epigenetics
Subjects:
nc886
Cardiometabolic disease
Imprinted gene
DNA methylation
vtRNA2-1
Online Access:https://doi.org/10.1186/s13148-025-01871-7
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https://doi.org/10.1186/s13148-025-01871-7

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