Colchicine Does Not Reduce Abdominal Aortic Aneurysm Growth in a Mouse Model

Background and Aims. The nacht domain, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) inflammasome is upregulated in human abdominal aortic aneurysm (AAA), but its pathogenic role is unclear. The aims of this study were firstly to examine whether the inflammasome was upregulated...

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Main Authors: James Phie, Shivshankar Thanigaimani, Pacific Huynh, Raghuveeran Anbalagan, Corey S. Moran, Robert Kinobe, Joseph V. Moxon, Matt A. Field, Smriti M. Krishna, Jonathan Golledge
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Cardiovascular Therapeutics
Online Access:http://dx.doi.org/10.1155/2022/5299370
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