Brucella-induced activation of AIM2 inflammasome and Caspase-1 enhances IL-18 secretion in THP-1 cells

Introduction/Objective. The purpose was to investigate the role of the inflammasome absent in melanoma 2 (AIM2) in Brucella-induced inflammatory responses in macrophages. Methods. A cell model of Brucella infection was established using a human macrophage cell line. Real-time quantitative polymerase...

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Bibliographic Details
Main Authors: Li Yupu, Zhang Zhaojing, Zhao Pengfei, Qiao Pengfei
Format: Article
Language:English
Published: Serbian Medical Society 2025-01-01
Series:Srpski Arhiv za Celokupno Lekarstvo
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Online Access:https://doiserbia.nb.rs/img/doi/0370-8179/2025/0370-81792500015L.pdf
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