Data structures for compound promiscuity analysis: promiscuity cliffs, pathways and promiscuity hubs formed by inhibitors of the human kinome

Aim: A large collection of promiscuity cliffs (PCs), PC pathways (PCPs) and promiscuity hubs (PHs) formed by inhibitors of human kinases is made freely available. Methodology: Inhibitor PCs were systematically identified and organized in network representations, from which PCPs were extracted. PH co...

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Bibliographic Details
Main Authors: Filip Miljković, Jürgen Bajorath
Format: Article
Language:English
Published: Taylor & Francis Group 2019-08-01
Series:Future Science OA
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Online Access:https://www.future-science.com/doi/10.2144/fsoa-2019-0040
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