Stability-based approaches in chemoproteomics

Target deconvolution can help understand how compounds exert therapeutic effects and can accelerate drug discovery by helping optimise safety and efficacy, revealing mechanisms of action, anticipate off-target effects and identifying opportunities for therapeutic expansion. Chemoproteomics, a combin...

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Bibliographic Details
Main Authors: Amy L. George, Maria Emilia Dueñas, José Luis Marín-Rubio, Matthias Trost
Format: Article
Language:English
Published: Cambridge University Press 2024-01-01
Series:Expert Reviews in Molecular Medicine
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S1462399424000061/type/journal_article
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