Classification of Parkinson’s disease and isolated REM sleep behaviour disorder: delineating progression markers from the sebum volatilome

Classification of Parkinson’s disease and isolated REM sleep behaviour disorder: delineating progression markers from the sebum volatilome

Abstract Parkinson’s Disease (PD) has been associated with a distinct odour, emanating from the skin and strongest in sebum-rich areas. Here, volatile components from sebum were analysed directly with Thermal Desorption Gas Chromatography - Mass Spectrometry. We analysed samples from subjects with c...

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Main Authors: Caitlin Walton-Doyle, Beatrice Heim, Eleanor Sinclair, Sze Hway Lim, Katherine A. Hollywood, Joy Milne, Evi Holzknecht, Ambra Stefani, Birgit Högl, Klaus Seppi, Monty Silverdale, Werner Poewe, Perdita Barran, Drupad K. Trivedi
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-025-01026-8
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https://doi.org/10.1038/s41531-025-01026-8

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