Inhibition mediated by group III metabotropic glutamate receptors regulates habenula activity and defensive behaviors

Inhibition mediated by group III metabotropic glutamate receptors regulates habenula activity and defensive behaviors

Abstract Inhibition plays a key role in brain functions. While typically linked to GABA, inhibition can be induced by glutamate via metabotropic glutamate receptors (mGluRs). Here, we investigated the role of mGluR-mediated inhibition in the habenula, a conserved, glutamatergic brain hub involved in...

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Main Authors: Anna Maria Ostenrath, Nicholas Faturos, Yağnur Işık Çiftci Çobanoğlu, Bram Serneels, Inyoung Jeong, Ekin Dongel Dayanc, Anja Enz, Francisca Hinrichsen, Aytac Kadir Mutlu, Ricarda Bardenhewer, Suresh Kumar Jetti, Stephan C. F. Neuhauss, Nathalie Jurisch-Yaksi, Emre Yaksi
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62115-z
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https://doi.org/10.1038/s41467-025-62115-z

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