Endoscopic variceal ligation combined with carvedilol versus endoscopic variceal ligation combined with propranolol for the treatment of oesophageal variceal bleeding in cirrhosis: study protocol for a multicentre, randomised controlled trial

Endoscopic variceal ligation combined with carvedilol versus endoscopic variceal ligation combined with propranolol for the treatment of oesophageal variceal bleeding in cirrhosis: study protocol for a multicentre, randomised controlled trial

Introduction Liver cirrhosis and its severe complication, oesophageal variceal bleeding (EVB), pose significant health risks. Standard treatment for EVB combines non-selective beta-blockers (NSBB) with endoscopic variceal ligation (EVL). Carvedilol, an NSBB with additional benefits, is preferred for...

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Main Authors: Jing Wang, Meng Li, Lei Wang, Li Zhang, Ling Yang, Jian Wang, Duolao Wang, Rong Wang, Ya Peng, Chao Ma, Yiling Li, Yi Chen, Jing Xu, Xiaolong Qi, Hua Ye, Zhendong Jin, Hongyun Zhao, Wei Yan, Liwei Zhang, Chuan Liu, Andres Cardenas, Li Du, Ying Song, Biao Xie, Zhi Wei, Jianzhou Li, Wenhui Zhang, Qinghua Pan, Huiling Xiang, Shaoting Zhang, Shuairan Zhang, Xuan Liang, Shengjuan Hu, Lijun Peng, Xiaojie Zhang, Jingyi Xu, Xiaochao Liu, Huanhai Xu, Zhixu Fan, Lichun Shao, Pengyuan He, Qianlong Li, Yunhai Wu, Liyao Zhang, Dianliang Fang, Quanke Li, Dongli Xia, Yuchen Lv, Zongchao Zhang, Chaoguang Yan, Yuxia Wan, Haiming Fang, Wenlong Yang, Xiangman Zhang, Wei Rao, Xiurong Xia, Qiang Qiao, Ruimiao Yu, Changzhen Ren, Yuejun Yang, Zhenzhen Zhai, Xuejin Liu, Xingjun Lu, Yansheng Jia
Format: Article
Language:English
Published: BMJ Publishing Group 2025-04-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/4/e093866.full
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