A core driver gene set identified based on geMER reveals its potential driver mechanism in pan-cancer

Abstract Increasing evidence underscores the driving role of coding and non-coding variants in cancer development. Analyzing gene sets in biological processes offers deeper insights into the molecular mechanisms of carcinogenesis. Here, we developed geMER to identify candidate driver genes genome-wi...

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Bibliographic Details
Main Authors: Jing Gan, Yuncong Wang, Zhuoran Shi, Haoyu Hu, Manyi Xu, Xinrong Li, Wenbo Dong, Jiaheng He, Yusen Zhao, Yakun Zhang, Yue Sun, Caiyu Zhang, Qianyi Lu, Shangwei Ning, Yan Jin, Hui Zhi
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-01060-y
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