Transcriptomic dynamics and cell-to-cell communication during the transition of prospermatogonia to spermatogonia revealed at single-cell resolution

Transcriptomic dynamics and cell-to-cell communication during the transition of prospermatogonia to spermatogonia revealed at single-cell resolution

Abstract Background Spermatogonia are essential for the continual production of sperm and regeneration of the entire spermatogenic lineage after injury. In mammals, spermatogonia are formed in the neonatal testis from prospermatogonia (also termed gonocytes), which are established from primordial ge...

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Bibliographic Details
Main Authors: Zhen He, Rong-Ge Yan, Qin-Bang Shang, Qi-En Yang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Genomics
Subjects:
Prospermatogonia
Spermatogonia
Fate decisions
Single-cell RNA-seq
Transcription regulator
Online Access:https://doi.org/10.1186/s12864-025-11244-2
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https://doi.org/10.1186/s12864-025-11244-2

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