TRPM7 contributes to pyroptosis and its involvement in status epilepticus

TRPM7 contributes to pyroptosis and its involvement in status epilepticus

Abstract Background Pyroptosis, a novel form of programmed cell death, has been implicated in neurodegeneration diseases. However, its role in status epilepticus (SE)—a condition characterized by prolonged or repeated seizures—remains inadequately understood. Methods SE were induced by intraperitone...

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Main Authors: Xin Tong, Yu Tong, Jiahe Zheng, Ruixue Shi, Hongyue Liang, Meixuan Li, Yulu Meng, Jian Shi, Dongyi Zhao, Corey Ray Seehus, Jialu Wang, Xiaoxue Xu, Tomasz Boczek, Sayuri Suzuki, Andrea Fleig, Reinhold Penner, Naining Zhang, Jianjun Xu, Jingjing Duan, Zhiyi Yu, Wuyang Wang, Weidong Zhao, Feng Guo
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Neuroinflammation
Subjects:
NLRP3
Pyroptosis
SE
STAT3
TRPM7
Zn2+
Online Access:https://doi.org/10.1186/s12974-024-03292-4
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https://doi.org/10.1186/s12974-024-03292-4

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