Cell-Free DNA (cfDNA) Regulates Metabolic Remodeling, Sustaining Proliferation, Quiescence, and Migration in MDA-MB-231, a Triple-Negative Breast Carcinoma (TNBC) Cell Line

Cell-Free DNA (cfDNA) Regulates Metabolic Remodeling, Sustaining Proliferation, Quiescence, and Migration in MDA-MB-231, a Triple-Negative Breast Carcinoma (TNBC) Cell Line

<b>Background:</b> The clinical relevance of circulating cell-free DNA (cfDNA) in oncology has gained significant attention, with its potential as a biomarker for cancer diagnosis and monitoring. However, its precise role in cancer biology and progression remains unclear. cfDNA in cancer...

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Bibliographic Details
Main Authors: Isabel Lemos, Catarina Freitas-Dias, Ana Hipólito, José Ramalho, Fabrizio Carteni, Luís G. Gonçalves, Stefano Mazzoleni, Jacinta Serpa
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Metabolites
Subjects:
cell-free DNA (cfDNA)
metabolic remodeling
cell proliferation
quiescence
migration
toll-like receptor 9 (TLR9)
Online Access:https://www.mdpi.com/2218-1989/15/4/227
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