Explainable artificial intelligence of DNA methylation-based brain tumor diagnostics

Abstract We have recently developed a machine learning classifier that enables fast, accurate, and affordable classification of brain tumors based on genome-wide DNA methylation profiles that is widely employed in the clinic. Neuro-oncology research would benefit greatly from understanding the under...

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Bibliographic Details
Main Authors: Salvatore Benfatto, Martin Sill, David T. W. Jones, Stefan M. Pfister, Felix Sahm, Andreas von Deimling, David Capper, Volker Hovestadt
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57078-0
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