Globus pallidus externus correlates with arousal in disorders of consciousness: a resting-state functional MRI study

Globus pallidus externus correlates with arousal in disorders of consciousness: a resting-state functional MRI study

IntroductionThe “Mesocircuit” model explains consciousness loss and recovery following severe brain injury as disconnection of cortical-subcortical circuits. Excessive inhibition of prefrontal cortex/thalamus by internal globus pallidus (GPi) is proposed as key to disorders of consciousness (DoC). H...

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Bibliographic Details
Main Authors: Xuqiu Qin, Yi Li, Kangkang Bai, Jiayi Miao, Xiaoyu Yanghao, Jiangli Cui, Xiaoling Zhang, Xingyu Miao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Neuroscience
Subjects:
disorders of consciousness
arousal
globus pallidus externus
Mesocircuit hypothesis
resting-state functional MRI
function connectivity
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1612271/full
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https://www.frontiersin.org/articles/10.3389/fnins.2025.1612271/full

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